Heparin-induced thrombocytopenia and thrombosis in ischemic stroke

Plasmapheresis in heparin-induced thrombocytopenia and thrombosis.

To the Editor: Thrombosis associated with severe thrombocytopenia is an infrequent, but life-threatening side effect of heparin therapy, which can involve any venous or arterial territory including the cerebral circulation. The treatment of this serious complication has not been satisfactorily resolved. Recently, Becker and Miller reviewed heparin-induced thrombocytopenia with thromboembolism a...

Heparin induced thrombocytopenia

Abstract Background and Objectives Heparin is still a commonly used anticoagulant in prophylaxis and treatment of thromboembolic events. Heparin-induced thrombocytopenia (HIT) is a life-threating adverse drug reaction of heparin. The diagnosis of HIT is made based on two important criteria, firstly clinical evaluation and secondly laboratory testing. In this comprehensive review, the authors w...

How I treat heparin-induced thrombocytopenia and thrombosis.

Heparin induced thrombocytopenia thrombosis (HIT/T) syndrome: diagnosis and treatment.

Heparin induced thrombocytopenia thrombosis (HIT/T) is associated with a high morbidity and mortality. Diagnosis is essentially clinical and negative results of laboratory assays do not exclude the diagnosis. Treatment involves stopping all heparin immediately and giving an alternative thrombin inhibitor. The adoption of low molecular weight heparins is one reason for the reduced incidence of t...

Heparin-induced thrombocytopenia-associated thrombosis in pediatric intensive care patients.

BACKGROUND Heparin-induced thrombocytopenia (HIT), a well-known side effect of heparin therapy, occurs in 1% to 5% of adults exposed to heparin. Of those, about 29% to 88% develop thrombosis. Most data on HIT-associated thrombosis in children are confined to anecdotal reports. OBJECTIVE To determine the incidence of HIT-associated thrombosis in heparin-exposed children. METHODS We performed...